| NCT02212249 |
Soluble VE-cadherin and VE-cadherin Antibody in Sclerodermic Sclerosis |
https://ClinicalTrials.gov/show/NCT02212249 |
Completed |
University Hospital, Grenoble |
2016-03-31 |
| NCT04166552 |
Evaluation of Safety, Tolerability and Preliminary Efficacy of EHP-101 in Diffuse Cutaneous Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT04166552 |
Recruiting |
Emerald Health Pharmaceuticals Inc. |
2021-03-31 |
| NCT04137224 |
Safety and Pharmacokinetics of IgPro20 and IgPro10 in Adults With Systemic Sclerosis (SSc) |
https://ClinicalTrials.gov/show/NCT04137224 |
Recruiting |
CSL Behring |
2021-08-31 |
| NCT03976648 |
A Clinical Study to Test Long Term Safety of GLPG1690 for Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03976648 |
Active, not recruiting |
Galapagos NV |
2022-05-31 |
| NCT03798366 |
A Clinical Study to Test How Effective and Safe GLPG1690 is for Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03798366 |
Completed |
Galapagos NV |
2020-05-21 |
| NCT03388255 |
Efficacy and Safety of PLACENTEX ® i.m. in Patients With Scleroderma Diseases |
https://ClinicalTrials.gov/show/NCT03388255 |
Active, not recruiting |
Mastelli S.r.l |
2019-09-30 |
| NCT03374618 |
Neutrophil Extracellular Traps in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03374618 |
Recruiting |
CHU de Reims |
2021-10-06 |
| NCT03294616 |
Transcutaneous Electroacupuncture for Gastric Complications of Scleroderma |
https://ClinicalTrials.gov/show/NCT03294616 |
Completed |
Johns Hopkins University |
2019-06-30 |
| NCT03274076 |
Evaluation of Tofacitinib in Early Diffuse Cutaneous Systemic Sclerosis (dcSSc) |
https://ClinicalTrials.gov/show/NCT03274076 |
Completed |
University of Michigan |
2019-04-08 |
| NCT03270722 |
Functional Luminal Imaging Probe (FLIP) Topography Use in Patients With Scleroderma and Trouble Swallowing |
https://ClinicalTrials.gov/show/NCT03270722 |
Recruiting |
Stanford University |
2020-05-31 |
| NCT03222492 |
Brentuximab Vedotin for Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03222492 |
Recruiting |
National Institute of Allergy and Infectious Diseases (NIAID) |
2020-09-30 |
| NCT03221257 |
Scleroderma Lung Study III - Combining Pirfenidone With Mycophenolate |
https://ClinicalTrials.gov/show/NCT03221257 |
Recruiting |
University of California, Los Angeles |
2021-12-31 |
| NCT03198689 |
Brentuximab Vedotin in Early Diffuse Cutaneous Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03198689 |
Recruiting |
Lawson Health Research Institute |
2021-03-01 |
| NCT03120533 |
Treprostinil Iontophoresis in Systemic Sclerosis Digital UlcErations. A Proof of Concept Study |
https://ClinicalTrials.gov/show/NCT03120533 |
Completed |
University Hospital, Grenoble |
2019-06-03 |
| NCT03092024 |
Scleroderma Patient-centered Intervention Network (SPIN) Hand Program Feasibility Study |
https://ClinicalTrials.gov/show/NCT03092024 |
Completed |
Lady Davis Institute |
2017-10-17 |
| NCT03060551 |
Injection of Autologous Adipose-derived Stromal Vascular Fraction in the Finger of Systemic Sclerosis Patients |
https://ClinicalTrials.gov/show/NCT03060551 |
Active, not recruiting |
Seoul St. Mary’s Hospital |
2020-03-31 |
| NCT03059979 |
The Effect of High Dose Methylprednisolone on Nailfold in Early Systemic Sclerosis ( SSc ) |
https://ClinicalTrials.gov/show/NCT03059979 |
Recruiting |
Radboud University |
2021-07-01 |
| NCT03058887 |
The Effects of Exercise in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03058887 |
Completed |
Sheffield Hallam University |
2018-09-30 |
| NCT03041025 |
Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03041025 |
Active, not recruiting |
GlaxoSmithKline |
2020-07-02 |
| NCT03027674 |
Topical 10 % Nifedipine Versus 5% Sildenafil in Secondary Raynaud |
https://ClinicalTrials.gov/show/NCT03027674 |
Completed |
Pontificia Universidad Catolica de Chile |
2016-08-31 |
| NCT03007004 |
Effect and Safety of Local Injection of Botulinum Toxin Type B Against Digital Ulcer in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03007004 |
Completed |
Gunma University |
2019-05-14 |
| NCT02975960 |
ADMSCs for the Treatment of Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02975960 |
Completed |
The Catholic University of Korea |
2017-10-30 |
| NCT02921971 |
Effectiveness and Safety of SAR156597 in Treating Diffuse Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02921971 |
Completed |
Sanofi |
2019-01-14 |
| NCT02915835 |
Riociguat in Scleroderma Associated Digital Ulcers |
https://ClinicalTrials.gov/show/NCT02915835 |
Completed |
University of Michigan |
2018-07-24 |
| NCT02896205 |
Study to Compare the Efficacy of Mycophenolate Mofetil in Systemic Sclerosis Related Early Interstitial Lung Disease |
https://ClinicalTrials.gov/show/NCT02896205 |
Completed |
Postgraduate Institute of Medical Education and Research |
2017-07-01 |
| NCT02837549 |
Novel Rehabilitation Strategies to Improve Arm Function in Patients With Scleroderma |
https://ClinicalTrials.gov/show/NCT02837549 |
Completed |
University of Michigan |
2017-09-30 |
| NCT02801305 |
Diltiazem Gel Versus Nitroglycerin Ointment in Healing Process of Scleroderma Digital Ulcers |
https://ClinicalTrials.gov/show/NCT02801305 |
Completed |
Shiraz University of Medical Sciences |
2017-01-31 |
| NCT02733978 |
Ozone Therapy in the Treatment of Digital Ulcers in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02733978 |
Completed |
Assiut University |
2016-08-31 |
| NCT02682511 |
Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT02682511 |
Recruiting |
Cumberland Pharmaceuticals |
2020-12-31 |
| NCT02663895 |
Safety and Efficacy of Oral Treprostinil in the Treatment of Calcinosis in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02663895 |
Completed |
Stanford University |
2020-05-31 |
| NCT02636127 |
Role of Circulating Cytotoxic Lymphocytes in Endothelial Cell Injury in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02636127 |
Completed |
Assistance Publique Hopitaux De Marseille |
2016-07-21 |
| NCT02610842 |
Hands on - a Hand Care Guide in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02610842 |
Completed |
University of Campinas, Brazil |
2015-10-31 |
| NCT02597933 |
A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung Fibrosis |
https://ClinicalTrials.gov/show/NCT02597933 |
Completed |
Boehringer Ingelheim |
2018-10-31 |
| NCT02562079 |
Vasculopathy, Inflammation and Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02562079 |
Completed |
University Hospital, Bordeaux |
2016-12-31 |
| NCT02503644 |
Proof-of-concept Trial of IVA337 in Diffuse Cutaneous Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02503644 |
Completed |
Inventiva Pharma |
2018-10-31 |
| NCT02494401 |
Taking Charge of Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02494401 |
Completed |
University of Michigan |
2017-07-28 |
| NCT02480335 |
The Clinical And Subclinical Effects on Arterial Stiffness of Bosentan in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02480335 |
Completed |
University Medical Center Groningen |
2018-07-30 |
| NCT02472743 |
Light Treatment for Scleroderma Finger Ulcers |
https://ClinicalTrials.gov/show/NCT02472743 |
Completed |
University of Manchester |
2016-01-31 |
| NCT02465437 |
Safety, Tolerability, Efficacy, and Pharmacokinetics of JBT-101 in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02465437 |
Active, not recruiting |
Corbus Pharmaceuticals Inc. |
2016-10-31 |
| NCT02453256 |
A Study of the Efficacy and Safety of Tocilizumab in Participants With Systemic Sclerosis (SSc) |
https://ClinicalTrials.gov/show/NCT02453256 |
Completed |
Hoffmann-La Roche |
2018-01-15 |
| NCT02426229 |
Safety & Suitability of Dabigatran to Inhibit Thrombin in Scleroderma |
https://ClinicalTrials.gov/show/NCT02426229 |
Completed |
Medical University of South Carolina |
2018-06-30 |
| NCT02396238 |
Scleroderma Treatment With Celution Processed Adipose Derived Regenerative Cells (STAR) |
https://ClinicalTrials.gov/show/NCT02396238 |
Completed |
Cytori Therapeutics |
2017-09-19 |
| NCT02386436 |
A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of GSK2330811 in Healthy Subjects |
https://ClinicalTrials.gov/show/NCT02386436 |
Completed |
GlaxoSmithKline |
2016-04-11 |
| NCT02371005 |
Oral Manifestations of Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02371005 |
Recruiting |
University Hospital, Strasbourg, France |
2021-06-30 |
| NCT02370784 |
Atorvastatin for Microvascular Endothelial Function and Raynaud in Early Diffuse Scleroderma |
https://ClinicalTrials.gov/show/NCT02370784 |
Active, not recruiting |
University of Pittsburgh |
2018-12-15 |
| NCT02370693 |
Comparing and Combining Bortezomib and Mycophenolate in SSc Pulmonary Fibrosis |
https://ClinicalTrials.gov/show/NCT02370693 |
Recruiting |
Northwestern University |
2020-06-30 |
| NCT02363478 |
Long Term Effect of Buspirone on Esophageal Function and Esophageal Symptoms in Patients With Systematic Sclerosis (SSc) |
https://ClinicalTrials.gov/show/NCT02363478 |
Completed |
Laikο General Hospital, Athens |
2015-09-30 |
| NCT02349009 |
Trial of Topical C-82 in Systemic Sclerosis - A Phase I/II Biomarker and Safety Trial |
https://ClinicalTrials.gov/show/NCT02349009 |
Completed |
Prism Pharma Co., Ltd. |
2016-07-31 |
| NCT02290613 |
Early Treatment of Borderline Pulmonary Arterial Hypertension Associated With Systemic Sclerosis (SSc-APAH) |
https://ClinicalTrials.gov/show/NCT02290613 |
Completed |
Heidelberg University |
2017-11-27 |
| NCT02283762 |
Efficacy and Safety of Riociguat in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02283762 |
Completed |
Bayer |
2017-12-15 |
| NCT02260557 |
Effects of Selexipag in Adults With Raynaud’s Phenomenon Secondary to Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02260557 |
Completed |
Actelion |
2015-04-30 |
| NCT02228850 |
Study of Acute Peripheral Vascular Effects, Safety and Tolerability in Subjects With Raynaud’s Phenomenon Secondary to Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02228850 |
Completed |
NexMed (U.S.A.), Inc. (subsidiary of Apricus Biosciences, Inc.) |
2015-06-30 |
| NCT02165111 |
Efficacy of Botulinum Toxin In Scleroderma-Associated Raynaud’s Syndrome |
https://ClinicalTrials.gov/show/NCT02165111 |
Completed |
Johns Hopkins University |
2015-09-30 |
| NCT02161406 |
A Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT02161406 |
Completed |
University of Michigan |
2018-09-12 |
| NCT01309997 |
Imatinib and Rituximab in Treating Cutaneous Sclerosis in Patients With Chronic Graft-Versus-Host Disease |
https://ClinicalTrials.gov/show/NCT01309997 |
Completed |
Fred Hutchinson Cancer Research Center |
2014-12-31 |
| NCT01295736 |
Sildenafil Effect on Digital Ulcer Healing in sClerodErma SEDUCE STUDY |
https://ClinicalTrials.gov/show/NCT01295736 |
Completed |
University Hospital, Lille |
2013-08-31 |
| NCT01284322 |
Fresolimumab In Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01284322 |
Completed |
Boston University |
2013-06-30 |
| NCT02047708 |
Zibotentan Better Renal Scleroderma Outcome Study |
https://ClinicalTrials.gov/show/NCT02047708 |
Completed |
University College, London |
2017-10-31 |
| NCT01933334 |
Safety and Tolerability of Pirfenidone in Participants With Systemic Sclerosis−Related Interstitial Lung Disease (SSc-ILD) (LOTUSS) |
https://ClinicalTrials.gov/show/NCT01933334 |
Completed |
Genentech, Inc. |
2014-09-30 |
| NCT01895244 |
Autologous Stem Cell Transplantation for Progressive Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01895244 |
Recruiting |
University Hospital Tuebingen |
2020-09-30 |
| NCT01878526 |
Gastroesophageal Reflux Treatment in Scleroderma |
https://ClinicalTrials.gov/show/NCT01878526 |
Completed |
Khon Kaen University |
2015-08-31 |
| NCT01862926 |
Rituximab Versus Cyclophosphamide in Connective Tissue Disease-ILD |
https://ClinicalTrials.gov/show/NCT01862926 |
Active, not recruiting |
Royal Brompton & Harefield NHS Foundation Trust |
2020-08-31 |
| NCT01813578 |
Effects of Intensive Aerobic and Muscle Endurance Exercise in Patients With Systemic Sclerosis - a Pilot Study |
https://ClinicalTrials.gov/show/NCT01813578 |
Completed |
Karolinska University Hospital |
2010-04-30 |
| NCT01813279 |
Assessment of the Subcutaneous Reinjection of Human Autologous Adipose-derived Stromal Vascular Fraction (Celution® System) in the Hands of Patients Suffering From Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01813279 |
Completed |
Assistance Publique Hopitaux De Marseille |
2013-11-30 |
| NCT01804959 |
Clinical Trial of Probiotics in Systemic Sclerosis Associated Gastrointestinal Disease |
https://ClinicalTrials.gov/show/NCT01804959 |
Active, not recruiting |
Singapore General Hospital |
2017-11-30 |
| NCT01799174 |
Treatment Study Comparing UVA-1 Phototherapy Versus Placebo Treatment for Morphea |
https://ClinicalTrials.gov/show/NCT01799174 |
Completed |
University of Texas Southwestern Medical Center |
2015-05-31 |
| NCT01748084 |
Rituximab in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01748084 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2016-04-18 |
| NCT01743612 |
Laser Speckle Contrast Imaging for Cutaneous Microvascular Dysfunction Detection in Systemic Sclerosis. |
https://ClinicalTrials.gov/show/NCT01743612 |
Completed |
University Hospital, Grenoble |
2015-06-30 |
| NCT01670565 |
Belimumab for the Treatment of Diffuse Cutaneous Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01670565 |
Completed |
Hospital for Special Surgery, New York |
2015-11-30 |
| NCT01651143 |
Proof of Biological Activity of SAR100842 in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01651143 |
Completed |
Sanofi |
2013-11-30 |
| NCT04335279 |
Evaluation of the Scleroderma Patient-centered Intervention Network COVID-19 Home-isolation Activities Together Program |
https://ClinicalTrials.gov/show/NCT04335279 |
Active, not recruiting |
Lady Davis Institute |
2020-06-03 |
| NCT01570764 |
Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease |
https://ClinicalTrials.gov/show/NCT01570764 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2018-02-22 |
| NCT01553981 |
A Trial of Tadalafil in Interstitial Lung Disease of Scleroderma |
https://ClinicalTrials.gov/show/NCT01553981 |
Completed |
Sanjay Gandhi Postgraduate Institute of Medical Sciences |
2014-04-30 |
| NCT01538719 |
IL1-TRAP, Rilonacept, in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01538719 |
Completed |
Boston University |
2017-01-31 |
| NCT01532869 |
A Study of RoActemra/Actemra (Tocilizumab) Versus Placebo in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01532869 |
Completed |
Hoffmann-La Roche |
2014-01-31 |
| NCT01488214 |
Neuropsychiatric Scleroderma Study: Systematic Evaluation of Neuropsychiatric Involvement in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01488214 |
Completed |
University Hospital, Lille |
2017-10-24 |
| NCT01487551 |
An Open-Label Study to Evaluate Biomarkers and Safety in Systemic Sclerosis Patients Treated With ABR-215757 (Paquinimod) |
https://ClinicalTrials.gov/show/NCT01487551 |
Completed |
Active Biotech AB |
2013-02-28 |
| NCT01474109 |
Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients |
https://ClinicalTrials.gov/show/NCT01474109 |
Completed |
Actelion |
2013-11-30 |
| NCT01413100 |
Scleroderma Treatment With Autologous Transplant (STAT) Study |
https://ClinicalTrials.gov/show/NCT01413100 |
Active, not recruiting |
Fred Hutchinson Cancer Research Center |
2025-01-31 |
| NCT01395732 |
Bosentan in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01395732 |
Completed |
Actelion |
2012-11-30 |
| NCT01347008 |
Effect of Sildenafil on the Microcirculatory Blood Flow and Endothelial Progenitor Cells in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01347008 |
Completed |
Federal University of São Paulo |
2013-01-31 |
| NCT04401943 |
Online Fatigue Intervention Program for People With Scleroderma |
https://ClinicalTrials.gov/show/NCT04401943 |
Recruiting |
University of New Mexico |
2021-04-30 |
| NCT04388176 |
Cold Challenge With C21 in RP |
https://ClinicalTrials.gov/show/NCT04388176 |
Active, not recruiting |
Vicore Pharma AB |
2020-10-01 |
| NCT04368403 |
A Study of KHK4827 in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT04368403 |
Active, not recruiting |
Kyowa Kirin Co., Ltd. |
2019-01-31 |
| NCT04336475 |
The Effect of a Home-based Orofacial Exercise Program on Oral Aperture of Systemic Sclerosis Patients |
https://ClinicalTrials.gov/show/NCT04336475 |
Completed |
Cukurova University |
2019-01-31 |
| NCT04274257 |
A Study of the Efficacy and Safety of Rituximab in Participants With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT04274257 |
Completed |
Tokyo University |
2019-05-09 |
| NCT04273386 |
Mouth Handicap in Systemic Sclerosis Questionnaire (MHISS) in Turkish |
https://ClinicalTrials.gov/show/NCT04273386 |
Recruiting |
Istanbul University |
2021-01-20 |
| NCT04265144 |
Cohort of Patients With Systemic Sclerosis Within the Framework of the RESO Reference Centre |
https://ClinicalTrials.gov/show/NCT04265144 |
Recruiting |
University Hospital, Bordeaux |
2030-06-30 |
| NCT04214925 |
Effectiveness of Tai Chi Exercise Program in Scleroderma Patients |
https://ClinicalTrials.gov/show/NCT04214925 |
Completed |
Pamukkale University |
2019-06-20 |
| NCT04179292 |
The Effect of Physiotherapy Program in Scleroderma Patients |
https://ClinicalTrials.gov/show/NCT04179292 |
Recruiting |
Istanbul University |
2020-11-21 |
| NCT04138485 |
Efficacy and Safety of IgPro10 in Adults With Systemic Sclerosis (SSc) |
https://ClinicalTrials.gov/show/NCT04138485 |
Active, not recruiting |
CSL Behring |
2023-11-30 |
| NCT04118725 |
Muscular Respiratory Involvement and Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT04118725 |
Recruiting |
Poitiers University Hospital |
2021-08-31 |
| NCT04045743 |
The Benefit of Bermekimab in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT04045743 |
Recruiting |
Hellenic Institute for the Study of Sepsis |
2021-02-01 |
| NCT04040322 |
Intravenous Iloprost in Subjects With Symptomatic Raynaud’s Phenomenon Secondary to Systemic Sclerosis (Phase 3) |
https://ClinicalTrials.gov/show/NCT04040322 |
Recruiting |
Eicos Sciences, Inc. |
2020-06-30 |
| NCT03965780 |
The SPIN - Scleroderma Support Group Leader EDucation Program Trial (SPIN-SSLED) |
https://ClinicalTrials.gov/show/NCT03965780 |
Recruiting |
Lady Davis Institute |
2021-02-28 |
| NCT03957681 |
A Phase 3 Study of KHK4827 in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03957681 |
Active, not recruiting |
Kyowa Kirin Co., Ltd. |
2021-04-01 |
| NCT03914781 |
SPIN Self-Management Feasibility Trial |
https://ClinicalTrials.gov/show/NCT03914781 |
Completed |
Lady Davis Institute |
2019-11-25 |
| NCT03867097 |
Intravenous Iloprost in Subjects With Symptomatic Raynaud’s Phenomenon Secondary to Systemic Sclerosis (Phase 2) |
https://ClinicalTrials.gov/show/NCT03867097 |
Completed |
Eicos Sciences, Inc. |
2019-09-30 |
| NCT03856853 |
Efficacy and Safety of Pirfenidone in Patient With Systemic Sclerosis-associated Interstitial Lung Disease |
https://ClinicalTrials.gov/show/NCT03856853 |
Recruiting |
Beijing Continent Pharmaceutical Co, Ltd. |
2021-02-10 |
| NCT03844061 |
Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03844061 |
Recruiting |
Hospital for Special Surgery, New York |
2022-02-28 |
| NCT03831438 |
Safety and Tolerability Study of AVID200 in Pts With Diffuse Cutaneous Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03831438 |
Active, not recruiting |
Formation Biologics |
2020-06-30 |
| NCT03817424 |
A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren’s Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis |
https://ClinicalTrials.gov/show/NCT03817424 |
Active, not recruiting |
Viela Bio |
2020-06-30 |
| NCT03816345 |
Nivolumab in Treating Patients With Autoimmune Disorders or Advanced, Metastatic, or Unresectable Cancer |
https://ClinicalTrials.gov/show/NCT03816345 |
Recruiting |
National Cancer Institute (NCI) |
2022-08-31 |
| NCT03766243 |
A Comparison Between Two Educational Methods in the Rehabilitation of the Microstomia in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03766243 |
Completed |
IRCSS Istituto Dermopatico dell’Immacolata, Fondazione Luigi Maria Monti |
2015-01-31 |
| NCT03742466 |
Local Injection of Ozone Versus Methylprednisolone Acetate in Carpal Tunnel Syndrome of Scleroderma Patients |
https://ClinicalTrials.gov/show/NCT03742466 |
Completed |
Assiut University |
2019-07-30 |
| NCT03726398 |
CompRehensive Phenotypic Characterization of Patients With Scleroderma-Associated ILD and PH |
https://ClinicalTrials.gov/show/NCT03726398 |
Recruiting |
University of Arizona |
2020-01-31 |
| NCT03717961 |
Efficacy of Botulinum Toxin A in Adult Subjects With Raynaud Phenomenon Secondary to Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03717961 |
Active, not recruiting |
Assistance Publique - Hôpitaux de Paris |
2020-07-31 |
| NCT03708718 |
Prednisolone in Early Diffuse Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03708718 |
Active, not recruiting |
University of Manchester |
2020-06-30 |
| NCT03692299 |
Effectiveness of Saccharomyces Boulardii for Gastrointestinal Bacterial-overgrowth in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03692299 |
Completed |
Coordinación de Investigación en Salud, Mexico |
2019-07-26 |
| NCT03675581 |
A Study to Test Whether Nintedanib Influences the Components of Birth-control Pills in Women With Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD) |
https://ClinicalTrials.gov/show/NCT03675581 |
Completed |
Boehringer Ingelheim |
2019-10-09 |
| NCT03644225 |
Suction Based Characterization of Healthy and Diseased Skin |
https://ClinicalTrials.gov/show/NCT03644225 |
Completed |
University of Zurich |
2019-06-04 |
| NCT03630211 |
Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03630211 |
Recruiting |
University of Pittsburgh |
2023-08-01 |
| NCT03614208 |
Individualized Home-based Exercise Program for Patient With Systemic Sclerosis. |
https://ClinicalTrials.gov/show/NCT03614208 |
Completed |
Universita di Verona |
2018-03-01 |
| NCT03593902 |
Cardiac Safe Transplants for Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03593902 |
Active, not recruiting |
Northwestern University |
2025-01-31 |
| NCT03588845 |
The Small Intestine Bacterial Overgrowth Study Pilot |
https://ClinicalTrials.gov/show/NCT03588845 |
Recruiting |
Canadian Scleroderma Research Group |
2021-04-01 |
| NCT03575156 |
Microparticles’s Role in the Pathophysiology of Systemic Lupus Erythematosus and Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03575156 |
Recruiting |
University Hospital, Bordeaux |
2021-09-30 |
| NCT03561233 |
Prevalence and Predictors of Proton Pump Inhibitor Partial Response in Gastroesophageal Reflux Disease in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03561233 |
Completed |
Khon Kaen University |
2018-05-31 |
| NCT03559465 |
Profibrosing Role of B Lymphocytes in Patients With Systemic Sclerosis. |
https://ClinicalTrials.gov/show/NCT03559465 |
Recruiting |
University Hospital, Lille |
2021-12-31 |
| NCT03558854 |
Evaluation of Effectiveness of Acetylsalicylic Acid on Markers of Vascular Dysfunction in Scleroderma Patients |
https://ClinicalTrials.gov/show/NCT03558854 |
Recruiting |
Federal University of São Paulo |
2020-02-29 |
| NCT03537105 |
Analysis of Cytokine Expression Pattern in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03537105 |
Completed |
Poitiers University Hospital |
2019-09-04 |
| NCT03531216 |
Topical Rosemary Oil Application in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03531216 |
Completed |
ARCIM Institute Academic Research in Complementary and Integrative Medicine |
2016-03-21 |
| NCT03508661 |
The Scleroderma Patient-centered Intervention Network (SPIN) Support Group Leader Education Program Feasibility Trial |
https://ClinicalTrials.gov/show/NCT03508661 |
Completed |
Lady Davis Institute |
2018-08-10 |
| NCT03508375 |
Evaluation of the Serum Soluble Fractalkine as a Biomarker of Pulmonary Fibrosis in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03508375 |
Recruiting |
Assistance Publique Hopitaux De Marseille |
2021-05-31 |
| NCT03482219 |
Rehabilitation for Arm Coordination and Hand Movement in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03482219 |
Active, not recruiting |
University of Michigan |
2020-09-30 |
| NCT03444220 |
Gut Microbiota Transplantation in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03444220 |
Completed |
Oslo University Hospital |
2018-05-18 |
| NCT03419208 |
Scleroderma Patient-centered Intervention Network (SPIN) Hand Program |
https://ClinicalTrials.gov/show/NCT03419208 |
Active, not recruiting |
Lady Davis Institute |
2020-03-01 |
| NCT01241383 |
Effect of Bosentan in Scleroderma Renal Crisis |
https://ClinicalTrials.gov/show/NCT01241383 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2015-10-31 |
| NCT01208792 |
Auto-immunity and Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT01208792 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2014-07-15 |
| NCT01166139 |
Nilotinib in the Treatment of Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01166139 |
Completed |
Hospital for Special Surgery, New York |
2014-07-31 |
| NCT01117298 |
A Randomized Control Trial to Assess the Efficacy of Tadalafil in Raynaud’s Phenomenon in Scleroderma |
https://ClinicalTrials.gov/show/NCT01117298 |
Completed |
Sanjay Gandhi Postgraduate Institute of Medical Sciences |
2010-04-30 |
| NCT01093885 |
Study of Ambrisentan With Antifibrotic Agent Combination Therapy in Diffuse Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01093885 |
Completed |
University of Pennsylvania |
2016-07-31 |
| NCT01086540 |
Rituximab for Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH) |
https://ClinicalTrials.gov/show/NCT01086540 |
Completed |
National Institute of Allergy and Infectious Diseases (NIAID) |
2018-06-05 |
| NCT01051960 |
Exercise Induced Pulmonary Hypertension in Systemic Sclerosis and Treatment With Ambrisentan |
https://ClinicalTrials.gov/show/NCT01051960 |
Completed |
University of California, Los Angeles |
2010-06-30 |
| NCT00984932 |
Effect of Rosuvastatin on Systemic Sclerosis-related Pulmonary Hypertension |
https://ClinicalTrials.gov/show/NCT00984932 |
Completed |
University of Alexandria |
2009-07-31 |
| NCT00946738 |
The Effect of Physical Therapy on Raynaud`s Phenomenon Secondary to Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00946738 |
Completed |
Charite University, Berlin, Germany |
2008-03-31 |
| NCT00946699 |
A Study of the Safety and Tolerability of MEDI-551 in Scleroderma |
https://ClinicalTrials.gov/show/NCT00946699 |
Completed |
MedImmune LLC |
2012-03-31 |
| NCT00930683 |
A Study to Evaluate Safety and Tolerability of Multiple Doses of MEDI-546 in Adult Subjects With Scleroderma |
https://ClinicalTrials.gov/show/NCT00930683 |
Completed |
MedImmune LLC |
2010-05-31 |
| NCT00909337 |
Early Therapy of Pulmonary Arterial Hypertension |
https://ClinicalTrials.gov/show/NCT00909337 |
Completed |
Medical University of Graz |
2010-06-30 |
| NCT00883129 |
Comparison of Therapeutic Regimens for Scleroderma Interstitial Lung Disease (The Scleroderma Lung Study II) |
https://ClinicalTrials.gov/show/NCT00883129 |
Completed |
University of California, Los Angeles |
2015-01-31 |
| NCT00848939 |
Pharmacokinetics of Oral Treprostinil in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00848939 |
Completed |
United Therapeutics |
2010-01-31 |
| NCT04387825 |
Safety Of Fat Micrografts With Adipose-Derived Stromal Vascular Fraction In Hands Of Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT04387825 |
Completed |
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran |
2019-05-31 |
| NCT01445821 |
Autologous Stem Cell Systemic Sclerosis Immune Suppression Trial |
https://ClinicalTrials.gov/show/NCT01445821 |
Active, not recruiting |
Northwestern University |
2020-12-31 |
| NCT03919799 |
KD025 in Subjects With Diffuse Cutaneous Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03919799 |
Recruiting |
Kadmon Corporation, LLC |
2021-12-31 |
| NCT03740724 |
A Study of FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma |
https://ClinicalTrials.gov/show/NCT03740724 |
Recruiting |
Fibrocell Technologies, Inc. |
2020-12-31 |
| NCT03398837 |
Trial to Evaluate Efficacy and Safety of Lenabasum in Diffuse Cutaneous Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT03398837 |
Active, not recruiting |
Corbus Pharmaceuticals Inc. |
2020-03-31 |
| NCT03141125 |
The Effect of Ethanol Extract Physalis Angulata Linn. in Scleroderma Patients With Standard Therapy |
https://ClinicalTrials.gov/show/NCT03141125 |
Completed |
Indonesia University |
2017-08-31 |
| NCT03207997 |
MRI Quantification of Pulmonary Fibrosis in Scleroderma Patients |
https://ClinicalTrials.gov/show/NCT03207997 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2018-03-09 |
| NCT01042158 |
A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT01042158 |
Completed |
Johns Hopkins University |
2014-11-30 |
| NCT00775463 |
Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine |
https://ClinicalTrials.gov/show/NCT00775463 |
Completed |
United Therapeutics |
2011-03-31 |
| NCT00764309 |
Safety Evaluation of Dasatinib in Subjects With Scleroderma Pulmonary Fibrosis |
https://ClinicalTrials.gov/show/NCT00764309 |
Completed |
Bristol-Myers Squibb |
2010-06-30 |
| NCT00740285 |
Effectiveness and Safety of Lidocaine for Scleroderma |
https://ClinicalTrials.gov/show/NCT00740285 |
Completed |
Federal University of São Paulo |
2006-04-30 |
| NCT00725361 |
A Study to Evaluate the Efficacy of an Oral Medication in the Treatment and Prevention of Digital Ulcers in Patients With Systemic Sclerosis (Scleroderma). |
https://ClinicalTrials.gov/show/NCT00725361 |
Completed |
Stanford University |
2010-12-31 |
| NCT00707187 |
Trial of IC351 in Female Scleroderma Patients With Raynaud’s and Sexual Dysfunction |
https://ClinicalTrials.gov/show/NCT00707187 |
Completed |
Rutgers, The State University of New Jersey |
2002-07-31 |
| NCT00704665 |
Recombinant Human Relaxin in the Treatment of Diffuse Scleroderma |
https://ClinicalTrials.gov/show/NCT00704665 |
Completed |
Rutgers, The State University of New Jersey |
2001-12-31 |
| NCT00697736 |
Cardiac Repercussion of Systemic Sclerodermias |
https://ClinicalTrials.gov/show/NCT00697736 |
Completed |
Hospices Civils de Lyon |
2014-12-31 |
| NCT00626665 |
Randomised Control Trial to Assess the Efficacy of Tadalafil in Raynaud’s Phenomenon in Scleroderma |
https://ClinicalTrials.gov/show/NCT00626665 |
Completed |
Sanjay Gandhi Postgraduate Institute of Medical Sciences |
2008-04-30 |
| NCT00624273 |
Sildenafil for Treatment of Digital Ulcers in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00624273 |
Completed |
Charite University, Berlin, Germany |
2004-11-30 |
| NCT00622895 |
Allogeneic Hematopoietic Cell Transplantation for Severe Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00622895 |
Completed |
Fred Hutchinson Cancer Research Center |
2011-11-01 |
| NCT00613171 |
Efficacy and Tolerability of STI571 (Imatinib Mesylate) for the Treatment of Fibrosis in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00613171 |
Completed |
Novartis |
2010-01-31 |
| NCT00574613 |
Efficacy and Safety Study of p144 to Treat Skin Fibrosis in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00574613 |
Completed |
ISDIN |
2009-11-30 |
| NCT00555581 |
Imatinib Mesylate (Gleevec) in the Treatment of Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00555581 |
Completed |
Hospital for Special Surgery, New York |
2011-12-31 |
| NCT00512902 |
A Study Using The Experimental Drug Called Imatinib (Gleevec) in Subjects With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00512902 |
Completed |
University of California, Los Angeles |
2008-11-30 |
| NCT00506831 |
Imatinib in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00506831 |
Completed |
Stanford University |
2010-09-30 |
| NCT00501995 |
High Dose Cyclophosphamide for Treatment of Scleroderma |
https://ClinicalTrials.gov/show/NCT00501995 |
Completed |
Johns Hopkins University |
2008-07-31 |
| NCT00498615 |
A Rho-kinase Inhibitor (Fasudil) in the Treatment of Raynaud’s Phenomenon |
https://ClinicalTrials.gov/show/NCT00498615 |
Completed |
Johns Hopkins University |
2012-03-31 |
| NCT00479934 |
Efficacy and Safety of Imatinib in Scleroderma |
https://ClinicalTrials.gov/show/NCT00479934 |
Completed |
University Hospital, Bordeaux |
2010-06-30 |
| NCT00476801 |
UVA1 Light for Treatment of Scleroderma and Similar Conditions |
https://ClinicalTrials.gov/show/NCT00476801 |
Completed |
University of Michigan |
2004-02-29 |
| NCT00442611 |
A Study to Evaluate the Safety and Efficacy of Abatacept in Patients With Diffuse Systemic Sclerosis (Scleroderma) |
https://ClinicalTrials.gov/show/NCT00442611 |
Completed |
Stanford University |
2011-06-30 |
| NCT00433186 |
Mycophenolate Mofetil in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00433186 |
Completed |
Boston University |
2011-03-31 |
| NCT00378521 |
Dose Response Study of a Topical Gel for the Treatment of Raynaud’s Phenomenon |
https://ClinicalTrials.gov/show/NCT00378521 |
Completed |
MediQuest Therapeutics |
NA |
| NCT00348296 |
Efficacy and Safety Study of GB-0998 for Treatment of Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00348296 |
Completed |
Benesis Corporation |
2009-07-31 |
| NCT00333437 |
Pulmonary Involvement in Scleroderma: A Clinical Study of the Safety and Efficacy of Mycophenolate Mofetil in Scleroderma Patients With Lung Involvement |
https://ClinicalTrials.gov/show/NCT00333437 |
Completed |
University of California, San Francisco |
2009-01-31 |
| NCT00319033 |
Open-label Study With Bosentan in Interstitial Lung Disease |
https://ClinicalTrials.gov/show/NCT00319033 |
Completed |
Actelion |
2006-02-28 |
| NCT00318188 |
Effects of a Personalized Standardized Rehabilitation Program in Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00318188 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2011-12-31 |
| NCT00318175 |
Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00318175 |
Completed |
Heinrich-Heine University, Duesseldorf |
NA |
| NCT00278525 |
Cyclophosphamide and rATG With Hematopoietic Stem Cell Support in Systemic Scleroderma |
https://ClinicalTrials.gov/show/NCT00278525 |
Completed |
Northwestern University |
2011-09-30 |
| NCT00241189 |
Rapamycin vs Methotrexate in Diffuse SSc |
https://ClinicalTrials.gov/show/NCT00241189 |
Completed |
University of California, Los Angeles |
2006-06-30 |
| NCT00147771 |
Imiquimod in Children With Plaque Morphea |
https://ClinicalTrials.gov/show/NCT00147771 |
Completed |
The Hospital for Sick Children |
2009-09-30 |
| NCT00129428 |
Ultraviolet B (UVB) Light Therapy in the Treatment of Skin Conditions With Altered Dermal Matrix |
https://ClinicalTrials.gov/show/NCT00129428 |
Completed |
University of Michigan |
2009-01-31 |
| NCT00114530 |
Scleroderma: Cyclophosphamide or Transplantation (SCOT) |
https://ClinicalTrials.gov/show/NCT00114530 |
Completed |
National Institute of Allergy and Infectious Diseases (NIAID) |
2016-04-30 |
| NCT00070590 |
Efficacy and Safety of Oral Bosentan in Pulmonary Fibrosis Associated With Scleroderma |
https://ClinicalTrials.gov/show/NCT00070590 |
Completed |
Actelion |
2005-09-30 |
| NCT00058578 |
Stem Cell Transplant to Treat Patients With Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00058578 |
Completed |
Baylor College of Medicine |
NA |
| NCT00043706 |
Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients With Early Stage Diffuse Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00043706 |
Completed |
Sanofi |
NA |
| NCT00025818 |
Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye Syndrome |
https://ClinicalTrials.gov/show/NCT00025818 |
Completed |
Allergan |
2003-03-31 |
| NCT00077584 |
Efficacy and Safety of Oral Bosentan on Healing/Prevention of Digital (Finger) Ulcers in Patients With Scleroderma |
https://ClinicalTrials.gov/show/NCT00077584 |
Completed |
Actelion |
2005-03-31 |
| NCT00016458 |
Phase II Pilot Study of Cyclophosphamide and Rabbit Anti-Thymocyte Globulin as Salvage Therapy in Patients With Diffuse Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00016458 |
Completed |
Office of Rare Diseases (ORD) |
NA |
| NCT00010335 |
Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders |
https://ClinicalTrials.gov/show/NCT00010335 |
Completed |
Fred Hutchinson Cancer Research Center |
2010-07-31 |
| NCT00007267 |
Psychological Treatments for Scleroderma |
https://ClinicalTrials.gov/show/NCT00007267 |
Completed |
Johns Hopkins University |
2006-06-30 |
| NCT00005675 |
Oral Type I Collagen for Relieving Scleroderma |
https://ClinicalTrials.gov/show/NCT00005675 |
Completed |
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) |
2005-05-31 |
| NCT00004786 |
Phase III Randomized, Double-Blind, Placebo-Controlled Study of Oral Iloprost for Raynaud’s Phenomenon Secondary to Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00004786 |
Completed |
Office of Rare Diseases (ORD) |
NA |
| NCT00004563 |
Scleroderma Lung Disease |
https://ClinicalTrials.gov/show/NCT00004563 |
Completed |
The University of Texas Health Science Center, Houston |
2013-05-31 |
| NCT00004380 |
Phase II Study of Recombinant Relaxin for Progressive Systemic Sclerosis |
https://ClinicalTrials.gov/show/NCT00004380 |
Completed |
Office of Rare Diseases (ORD) |
NA |